In this Highlight, recent reports are presented featuring three unique catalysts—Ir-based, TXT, and Al-Salen—demonstrating how the EnT process can generate triplet diradicals to form attractive cyclic architectures via intramolecular cyclization. Extensive experimental and theoretical studies have provided valuable insights, informing future strategies and potential implementations.

Abstract

Energy transfer (EnT) catalysis has emerged as a powerful and unique tool in modern synthetic methodology, enabling the generation of carbon–carbon/heteroatom centered diradicals from judiciously designed substrates. This highlight offers insights into recent breakthroughs including intramolecular cyclization, underscoring their potential to construct structurally complex, and valuable molecular architectures.